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In mice, the waltzing allele (w) that causes the mouse to run in circles due to an inner ear defect is recessive to the non-waltzing allele (W). In an ideal mouse population exhibiting Hardy–Weinberg equilibrium of 150 mice, 15% of the alleles are non-waltzing. What is the frequency of the recessive allele? Record your answer as a whole number percentage.

5 years ago

Answered By Chelsea W

85%


5 years ago

Answered By Maikol S

97.75


5 years ago

Answered By Maikol S

From the first question of Hardy Weinberg equilibrium one may be able to find the percentages for dominant and recessive individuals:

p+q=1

However, from this equation, we can’t determine the percentage of dominant and recessive alleles.

Therefore, we must take into consideration the second equation of Hardy Weinberg equilibrium: 

p2 + 2pq + q2 = 1 

where: 

p2= homozygous dominant

2pq= heterozygous dominant 

q2= homozygous recessive 

The allele “q” shows up in the places in this equation, and this two must be take into consideration. 

Knowing that “p = 15% or 0.15 (from the information in the original question), and that “q = 85% or 0.85” (100% - 15 % = 85%), all we have to do now is substitute the decimal value for “q” (0.85) into the second equation of Hardy Weinberg equilibrium: 

2pq + q2 

2(0.15)(0.85) + (0.852) = 0.9775

Or

97.75% 

 

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