Nephrogenic diabetes insipidus is a condition where ADH is released by the posterior pituitary but the cells in the kidneys are unable to respond to ADH. This is in contrast to neurogenic diabetes insipidus where the body does not produce enough ADH. When the kidneys are unable to respond to ADH, the urine formation ______ and ADH secretion _______. Which of the following rows correctly completes the sentence above?

Select one:

Urine Formation ADH Secretion Increases Increases in response to decreased water retention

Urine Formation ADH Secretion Decreases Decreases in response to increased water retention

Urine Formation ADH Secretion Decreases Increases in response to increased blood pressure

Urine Formation ADH Secretion Increases Decreases in response to decreased blood pressure 

5 years ago

Answered By Gregory S

So with nephrogenic diabetes insipidus. It doesn't matter how much ADH there is. The kidneys are responding. So since there's no reaction to ADH. Urine formation increases. Because of the loss of water in the urine from increased urine production. The body releases more ADH. It's a vicious circle. 

To sum it up. Both urine production and ADH increases 

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